Delta-like protein 4 (DLL4), also known as Drosophila Delta homolog 4 (Delta4), contains one DSL domain and eight EGF-like domains. It is expressed in vascular endothelium and functions as a Notch ...
CTX-009 is a bispecific antibody that simultaneously targets Delta-like ligand 4 (DLL4) and vascular endothelial growth factor A (VEGF-A). This next generation angiogenesis inhibitor has completed a ...
Compass Therapeutics is developing antibody therapies for cancers, with their lead candidate being CTX-009, a dual inhibitor of VEGF-A and DLL4. The company has upcoming topline data from their ...
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