Could a gene regulatory network in gut microbes have evolved its elaborate and tightly regulated molecular machinery only to pump out antibiotics indiscriminately? Researchers from the Institute of ...

We know the genes, but not their functions.” To resolve this long-standing bottleneck in microbial research, a joint research ...

Large-scale protein and gene profiling have massively expanded the landscape of cancer-associated proteins and gene mutations, but it has been difficult to discern whether they play an active role in ...

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

A large genetic screen has revealed how stem cells transform into brain cells, exposing hundreds of genes that make this ...

Alex Marson of Gladstone and his collaborators at Stanford University developed a genomic mapping technique that helps close ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...

Gene-set analysis seeks to identify the biological mechanisms underlying groups of genes with shared functions. Large language models (LLMs) have shown promise in generating functional descriptions ...

A sweeping genetic screen reveals how the brain is built and exposes a hidden gene behind a newly discovered childhood brain ...

Knowledge graphs are a powerful tool for bringing together information from biological databases and linking what is already ...