Polyethylenimine (PEI)-assisted transfection is a mainstay in upstream processing (USP) for viral vector manufacturing. But recent developments are shifting it from a ...
Polyplus-transfection SA, a privately-held company developing innovative technologies for molecular and cellular biology, and Blue Sky BioServices, a contract research organization (CRO) providing ...
Polyplus-transfection SA, has announced that ExcellGene SA has signed an extended supply agreement for Polyplus-transfection polyethylenimine (PEI) based transfection reagents. Polyplus-transfection ...
Initially intended for the treatment of hereditary single-gene defects, most gene therapies are also aimed at acquired diseases such as cancer, cardiovascular, and neurodegenerative pathologies. The ...
“We are delighted to sign this license agreement with Roche Glycart AG, an innovative subsidiary of Roche, focused in the research and development of new engineered antibody-based products,” said Mark ...
Gene therapy involves the transfer of genetically modified materials into a patient's cells to correct abnormal genes associated with diseases (Sun, 2017). Recent advancements in gene therapy have ...
Accurate monitoring of nanoparticle size and growth is essential to ensure scalability in the development of transfection vectors for gene delivery. This study highlights how Spatially Resolved-DLS ...
Response Surface Methods Point the Way to Higher rAAV Yields at Lower Levels of Transfection Reagent
Adverum Biotechnologies describes a multifactor design of experiments methodology that can optimize rAAV vector production while maintaining a specified N/P ratio Researchers at Adverum ...
Adenovirus or naked plasmid DNA (pDNA) has been used to deliver the therapeutic gene into corpus cavernosum. However, the potential risks of viral vector and inefficiency of naked pDNA have limited ...
In new work, scientists in Australia have now successfully demonstrated the use of magnetofection for the delivery of malaria DNA vaccine. Malaria is a life-threatening disease caused by a parasite ...
Hinnah Campwala (left) is a Principal Scientist in the Cell Biology Development Group at Sartorius BioAnalytical Instruments (Michigan, USA). With a background in drug discovery and immune cell ...
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