The Substance is a 2024 body horror film written, directed, co-produced, and co-edited by Coralie Fargeat. It stars Demi Moore, Margaret Qualley, and Dennis Quaid.

SUBSTANCE definition: that of which a thing consists; physical matter or material. See examples of substance used in a sentence.

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Jan 3, 2015 · The meaning of SUBSTANCE is essential nature : essence. How to use substance in a sentence.

Any material that possesses physical properties is called a substance. The word also refers to the gist or main idea of something. If you remember the main point of a lesson, you've got the substance.

SUBSTANCE definition: 1. material with particular physical characteristics: 2. an illegal drug: 3. the most important…. Learn more.

Definition of substance noun in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more.

A drug, chemical, or other material (such as glue) that one is dependent on or uses habitually and that is often illegal or subject to government regulation: Which substance was he abusing?

the actual matter of a thing as opposed to its appearance:[uncountable] form and substance. Chemistry a particular kind of material, as of a definite chemical composition:[countable] a metallic substance.

Dec 14, 2025 · substance (third-person singular simple present substances, present participle substancing, simple past and past participle substanced) (rare, transitive) To give substance to; to …